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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38763c84d7620fb8343e7d830bde90c412b7f4a4fc4f1f5dbfe06a867972fbc' 
  AND token = 'sLf85cv6Lm0GFfKuS1n4AoBrbNTEz/47Rm7GyJaBI+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}