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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c51d70d82fa3da1f4e439c1b366ac882614f56eacc97c1c7f5bdfa8e4fc74d1' 
  AND token = 'zXBVpdR2s1xrJe9n2yNi0rzN/3SuZTvbvhuU8wOcUsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}