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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3f125a02d6756c1138155a264c012d335a8c26de6a33d7543026b673bfa2ca4' 
  AND token = 'H79PDB1ZzSmA2pcN7rEbZXfwkC1WK6GCXw98wFxmfJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}