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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111da6482c6ecf7a1ff3df6b8f16805ed8e13e67ee14507f16904cdcaa28a68f' 
  AND token = 'BXhKrKZ7BpLaprZ3ImCrmaktHuvjdJBZEZQtkzV/uqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}