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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49795b26b1cf99c6e83b3e50cae0d9a7a23f916fdbdab45d301419b9e2e8f9e8' 
  AND token = 'GsXm4Sj30a5krCoIDXsg4i9jlXc4BoqAD5Aupo+o4rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}