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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1beef9c2ec58cf392956af45af38f004dfd8e0cfd7debb2b9b70f4db4d10d8' 
  AND token = 'CfRdcx0cniXJl4bvN7P8d+JIIXc4b9oQwzxeeNFl3bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}