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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cb7ea193da003d53a51a97e2a9cf918b90b68bd6c7774b879ac1e660290d3a' 
  AND token = 'PcEmbLjZSNawr4FpzCgaiWKTaeNmjFK1A2JI5D3Tll0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}