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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca9526082602a5b54f5ed7c45f4b368a1f3486c4b0c4765e6845b1d037e8a62' 
  AND token = 'I5Wsg03QdZM+EjvTDALd82n9ttyPvTwcGmrd9mSLEO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}