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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f614f2e4c81e18dc0b86bd53cd58c683f30d3ba33935a206825000db406b10c' 
  AND token = 'zOUhydBzCM4VAeY1OJhgsqe2oOXuPsGK+4Mpn5MI1aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}