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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7659a46e488c75d6c013fd90d55cf053d20714dee5b1865febafa42a4a34d500' 
  AND token = '0et6FaH546Qdf7F2rD20Sd8vgvfuYwl2CrXhaeXh1SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}