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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659beef355cec40892ccc21df72a1f49ccd34d297b979c93ca577bcb143e31c5' 
  AND token = 'rXXXXb4sTQOPq76ForXHprO0dRpVeyrn5qyWDZdyHOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}