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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1a8752aa0984f06739bfdd31d4aaab7e6c2e12af0e13eb2bcd650e48fb43b8' 
  AND token = 'IIWHWRNaZS7vQi2jfBIKGsemGZV43oUGe0/ZEZx3V24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}