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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492a6daf7583dc11654b4c2f89576fbb24bf74ce88f36a1eb74290a8875e6155' 
  AND token = 'FyU8XVW3Jh22evh4yymFbD9gYIQ0PVGIJAPDGxynyxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}