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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e58f4867fc2444f3fc21a97d886d12235d448efb3153873a0f8c4ef523ceb09' 
  AND token = 'HdSsKhK+fgk0VafiUL9UsdXDAe+sh+1GmAM5ptJPi1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}