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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9b096b354e73e18b9e70cf2ab746f623d1ebcef10e6d6461aa85d08c613bf9' 
  AND token = 'QWhfFylsfWzZjaouHVepU+TzXrOTlQ1N/DR4bDlS8Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}