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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4099af34d0e4b92881227a075aa3fd356605a423d910f2f7e0a5ddfd44649c' 
  AND token = '3NSCds8Pg/V+lTDss5pdgxaM+lsBENa+YzvIOxym3Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}