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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee6554d4e468c4ef6084ede01d7d2e502aac0f3a2d4fddf1f855563ee273a20' 
  AND token = 'azTxyuwn+O5nzNzPg7RquYI8/eN5icNkgX++XS3WcdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}