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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e898da91abafdb8086bca7fe25abac8df1b0d70c0673dc270bc6477726738b' 
  AND token = 'DFOX8QUsc5Qr4kXmv2V78xK3dmzywlg4oP+N+GDfQnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}