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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d2cee6bd54fee1059fd0d2a85d14774c9daf081492ecdb14bda51c481c9682' 
  AND token = '2pny8212JnLZhYxrwcOWxrN/WVWu3eV70B+Zmx55yZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}