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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede9cb11a233168e0511bda7700084ed9e0b8a88e02d7e3bd92ea7861560dc52' 
  AND token = 'w8JNN3H9BVhxULtsOgVigBufsNno6pf2rCy+wI6T0/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}