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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dcd23c679349ce29c940516c704cb5d147b27aa0d2978ccaf58d006b2e4ac39' 
  AND token = '7mV0PmODJCK/bOO20gFUcoSsKWdogu9tHS2zB5fHHvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}