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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc9346b2a4a5b4b20ff2146892d2b8d7ce2e40b95ff7607a8f81a4a98169d28' 
  AND token = 'yZmcanQyAsS7GfGyU5qWZmKs6QK2vi/EW0zDk7B6IrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}