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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8499d03c98aa81f96bcb7358a6dabfce9be6f23f8b097c6f4014f0ea0a6810' 
  AND token = 'f/V18zlwxY0aBmMfcpDfDn1C1LcyPw70vncLXYuEjzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}