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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd1281da2611cbd76d37faac636290574d9406b03dbe51ad3aec04d3784c16c' 
  AND token = 's5paFamHWSFIPz4IeiOcukUikOCzT/GvBSBU2CKlaJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}