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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9125e688458ad581b8ed01c5c938cc2602f68b019a0be8c1b4b77b34ee367f5f' 
  AND token = 'JHZXS9Ypadb8jp4CwFh0Vi4XnWnM0H2TzKF59LT1rSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}