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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cf4de483191502bd4289d69f58448bee96ad30f0a6a95c9b76a48f8d2eb1d3' 
  AND token = 'Q87ck7qd161eoE7u3CiPyHriWtSATtaZOtBiIEr5PWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}