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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618b517c37cbc15e80c06eef9497e91f441d01892b03de6dbc788a55f1be65c1' 
  AND token = 'mDe0vkoJ8He396t5Wu/CkSS4GdBisFXoC6vTEvSiYAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}