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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db78b2850a73916667812929e54b41c71cb64b6c316323a3a63a3d16ac3530e2' 
  AND token = 'NXRYw61Xcms6tK3Gd4vEHuXjmUqibm5foie9N2VUjcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}