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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3c4180a0f9ae32fb0eac49da7513b17d997e3db42568f882b1f291cefa9b6a' 
  AND token = 'NgAF5zL/glZGU3hs6Z8lWUHmIHG9H81c75kheXmejXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}