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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c86984d3d9f7f34684ffbce84e60f5e68291ddf0d0818dd4919aca22fc732e5b' 
  AND token = 'HUS9GCZ2efdIJUJm0TptM0+8KoFdZUCb2xrZ04fC2rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}