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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1f09a004e9ddd9b709eb61626b209d84f66a4ca04c45b85cd3838d39a92f71' 
  AND token = 'A6D+XPoTr6j6wOc4jTQCaXnJxrqVedSC0E2H03isFco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}