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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8be24e12c8115c8401dda72736e3b3b05ff125e006cc17a4bbdac63a813ad275' 
  AND token = 'ojMYGt41i846U3523PsvXN1Rtm+TO5kUKkXjH6IKLck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}