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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb8c7adb5e1a23b9723569d0f188e9cc0f361f9d46dfbf47d348f9f73da93781' 
  AND token = 'HY/Sj06eHnPhoHPz5EQ3IUx5z35tUisjs+xbRLcI5LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}