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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85409913fb3d3779ae54b71bf7fe1986d1678f0871020c69cd7b2ab3167a03c5' 
  AND token = 'l66AvuQPPQIVLzvJLvRvvAKcxWc3OTLj6Tp80A7Y60g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}