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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7b675bdcff1adeff9f33ab8c3d4afc5eb8243ca822281add1d27a181a3445d' 
  AND token = 'NSBKLu1NQH2cnSifvHATyNDWrxHBL2+8hawU2XVP7Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}