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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5950d9a2263628e1ec67cbbef14f807c2ee09842a7a9fe980272476ae8c079fd' 
  AND token = 'uN7pAG7gyFAK4mWbN6xbQYUjD1pm2vG1lOy2TOWpXAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}