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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648b34e09ffb8847447136c1991adcb54dedb2424834da8394b472be8c65b520' 
  AND token = '4shoqfe5yBp2T/lscWrz6wa03CUGBHABVKLuZxMury8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}