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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45405f9a7d1be5c125324ecdfd250a446102f45ea6a5176c655a8923f2dbf89' 
  AND token = 'bVBurBPxv5mSrD1rGdFebgsfPnGLADj4K/RZF0SRSMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}