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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a579ffcbc20894e49d03e7c979c50388f42f9d1b73088be438cc0deabaa897c' 
  AND token = '2LuhYsU7Q3E2cPFh6yNR2yG4Aj8MTRP9NC7xoFNTvl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}