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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23625687c42a5b2c5c41a476e3d350aa19ebdae559b0e2c30e7c910b646aaa6f' 
  AND token = '2tuDM/xU0h7pRzYsAQ5IyoYv4Kn9qgWwd3B/W9cjdAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}