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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f162416513814033a0cd2f7bf7797b020f426c87952af3d0570fae37d8937f8b' 
  AND token = 'sEOKYcmbrEz3eFere6XtY+Iz0mQIuvlHi3sYynxAUNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}