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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a47241be1561aecffa7dcf102ac30be5f911fb9422e2dd65c259e3c9a227683' 
  AND token = 'N5Z17wsWuXkOvBf32uigSB/kED3sS/0g++fQ01zmAKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}