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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a5af76857fb0ffcf9b51c6b63dffc521aec0871939c6dbcbda022dca778404' 
  AND token = 'lLJYW4lbQ0X/b6j9uP1lKLIib9Aa6klDMi8mU0GI1Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}