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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0abc61f6aa89b1916cf6ceba8b8a2ee5d20a7fa34ec3016f664ee475a9164466' 
  AND token = 'Qye0ViXH+woI0Mr6nP24i1a5kw9XsMzkykU+TSHPaRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}