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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49642ac7af24dc61f4a5895e1231f7782f9097d9280f141c71d6602b330f9d06' 
  AND token = '4YYiK9l8ayLmlZ4CTxHMVFlJNSfjaOrwujnHd3oK0os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}