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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151aa61b5b2ec5a25db89c7b15aa4fa8a473d7f1fdf981deae60c3b725648280' 
  AND token = 'nBgjh+LCPpNbHOKk2nbWgrFluB+34oLuRqR+HPB5fbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}