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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0498ec0350391369ac39957e07bc86bb25044bfe90447043c0d43ac094a7fd65' 
  AND token = 'BU/OW9jkddmB2vD8QvRPZRu/ZK5c2tABojL6Eixt8gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}