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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc8c8129c465545819592a4f4c385a81fb24b5b381461c51d8e1e39e45b78c9' 
  AND token = 'QPD3poBUek79LeEFZsylVjrXLbgic5bWIawtuA0Z3pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}