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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7f6fde60f389601937cff7a18caaf1a4874c83ed0cc2562859ed6ffe81c0bd4' 
  AND token = 'GVLF/w/OIVTyj3oDNC3LaoKE8SB5VBsnNbT/AxkwXQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}