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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3605e4a152a2a3f6f758e0f69092c40ad2773463bde52bb923358889d1f92c55' 
  AND token = 'o9ylZmQRnMDPCyTowJcXJMWmoWSx/O7Zb9efVd2IGDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}